{{short description|Wikipedia list article}}
{{chemical engineering}}
This is a list of software used to simulate the material and energy balances of chemical process plants. Applications for this include design studies, engineering studies, design audits, debottlenecking studies, control system check-out, [[process simulation]], [[dynamic simulation]], [[Operator Training Simulator|operator training simulators]], pipeline management systems, production management systems, [[Digital twin|digital twins]].

{|class="wikitable sortable" style="margin-left: auto; margin-right: auto;"
! Software !! Developer !! Applications !! Operative system !! License !! URL
|-
|[[Advanced Simulation Library|Advanced Simulation Library (ASL)]]
|Avtech Scientific
|Process data validation and reconciliation, real-time optimization, virtual sensing and predictive control
|Windows, Linux, FreeBSD, Mac
|open-source ([https://github.com/AvtechScientific/ASL/blob/c39215b9f5e7f36d6cdb33dbf6705011b121d95b/LICENSE AGPLv3])
|[http://asl.org.il]
|-
|[[APMonitor]]
|APMonitor
|MATLAB/Python/Julia-based data reconciliation, real-time optimization, dynamic simulation and nonlinear predictive control
|Windows, Linux
|open-source ([https://github.com/APMonitor/apm_server/blob/fb6cf7393418ee0ceedfe35a2fcd6e8bc8cdb2c6/apm_linux/LICENSE BSD-2-Clause])
|[http://apmonitor.com/]
|-
|Apros
|[[Fortum]] and [[VTT Technical Research Centre of Finland]]
|Dynamic process simulation for power plants
|Windows
|closed-source
|[http://www.apros.fi/en/]
|-
|[[ASCEND]]
|ASCEND
|Dynamic process simulation, general purpose language
|Windows, BSD, Linux
|open-source ([https://web.archive.org/web/20170623052028/http://svn.ascend4.org/trunk/LICENSE.txt GPLv2])
|[http://ascend4.org/ASCEND_overview]
|-
|Aspen Custom Modeler (ACM)
|[[Aspen Technology]]
|Dynamic process simulation
|Windows
|closed-source
|[https://www.aspentech.com/en/products/pages/aspen-custom-modeler]
|-
|[[Aspen HYSYS]]
|[[Aspen Technology]]
|Process simulation and optimization
|Windows
|closed-source
|[https://www.aspentech.com/en/products/engineering/aspen-hysys]
|-
|Aspen Plus
|[[Aspen Technology]]
|Process simulation and optimization
|Windows
|closed-source
|[https://www.aspentech.com/products/engineering/aspen-plus]
|-
|ASSETT
|[[Kongsberg Digital]]
|Dynamic process simulation
|Windows
|closed-source
|[https://web.archive.org/web/20140315042115/http://www.kongsberg.com/en/kogt/offerings/software/assett/]
|-
|BatchColumn
|ProSim
|Simulation and Optimization of batch distillation columns
|Windows
|closed-source
|[https://www.prosim.net/en/product/batch-column-simulation-and-optimization-of-batch-distillation-columns/]
|-
|BATCHES
|Batch Process Technologies, Inc.
|Simulation of recipe driven multiproduct and multipurpose batch processes for applications in design, scheduling and supply chain management
|Linux
|closed-source
|[http://bptechs.com]
|-
|BatchReactor
|ProSim
|Simulation of chemical reactors in batch mode
|Windows  
|closed-source
|[https://www.prosim.net/en/product/batchreactor-simulation-of-chemical-reactors-in-batch-mode/]
|-
|BioSTEAM
|Yoel Cortes-Pena & BioSTEAM Development Group
|Design, simulation, and costing of biorefineries under uncertainty
|Windows, Mac, Linux
|open-source ([https://github.com/BioSTEAMDevelopmentGroup/biosteam/blob/cca6df548b22c7bbbde10fae68f730f832485355/LICENSE.txt BSD-3-Clause])
|[https://biosteam.readthedocs.io/en/latest/]
|-
|CADSIM Plus
|Aurel Systems Inc.
|Steady-state and dynamic process simulation
|Windows
|closed-source
|[https://web.archive.org/web/20160305011501/http://www.aurelsystems.com/csplus.htm]
|-
|ChromWorks
|YPSO-FACTO
|Chromatographic process design, simulation & optimization
|Windows
|closed-source
|[http://www.ypso-facto.com]
|-
|CHEMCAD
|Chemstations
|Software suite for process simulation
|Windows
|closed-source
|[http://www.chemstations.com/Products/What_is_CHEMCAD/]
|-
|CHEMPRO
|EPCON
|Process Flow Simulation, Fluid Flow Simulation, & Process Equipment Sizing
|Windows 
|closed-source
|[http://www.epcon.com/chempro.html]
|-
|Cycad Process
|CM Solutions
|Process simulation and drawing package for minerals and metallurgical fields
|Windows
|closed-source
|[https://cycadprocess.com/]
|-
|Cycle-Tempo
|Asimptote
|Thermodynamic analysis and optimization of systems for the production of electricity, heat and refrigeration
|Windows
|closed-source
|[http://www.asimptote.nl/software/cycle-tempo/]
|-
|[[COCO simulator]] + ChemSep
|AmsterCHEM
|Steady state process simulation based on [[CAPE-OPEN Interface Standard]]
|Windows
|open-source ([https://www.cocosimulator.org/index_disclaimer.html Coco License 3.4])
|[http://www.cocosimulator.org/] [http://www.chemsep.org]
|-
|D-SPICE
|[[Kongsberg Digital]]
|Dynamic process simulation
|Windows
|closed-source
|[https://www.kongsberg.com/digital/products/process-simulation/]
|-
|[[Design II for Windows]]
|WinSim Inc.
|Process simulation
|Windows
|closed-source
|[http://www.winsim.com/design.html]
|-
|Distillation expert trainer
|ATR
|Operator training simulator for distillation process
|
|closed-source
|[https://web.archive.org/web/20110716093320/http://smartprocedures.com/distillation_expert]
|-
|[[Dymola]]
|[[Dassault Systèmes]]
|Modelica-based dynamic modelling and simulation software
|Windows, Linux
|closed-source
|[http://www.3ds.com/products-services/catia/capabilities/systems-engineering/modelica-systems-simulation/dymola]
|-
|DynoChem
|Scale-up Systems
|Dynamic process simulation and optimization
|Windows
|closed-source
|[https://www.scale-up.com/Dynochem]
|-
|DYNSIM
|[[Aveva|AVEVA]]
|Dynamic process simulation
|Windows
|closed-source
|
|-
|Dyssol<ref>{{Cite journal|date=2020-07-01|title=Dyssol—An open-source flowsheet simulation framework for particulate materials|url=https://www.sciencedirect.com/science/article/pii/S2352711020302855|journal=SoftwareX|language=en|volume=12|pages=100572|doi=10.1016/j.softx.2020.100572|issn=2352-7110}}</ref>
|
|Dynamic flowsheet simulation of solids processes
|Windows
|open-source ([https://github.com/FlowsheetSimulation/Dyssol-open/blob/53eb7b589ad03eb477d743ee6a90ee10297a9366/LICENSE BSD-3-Clause])
|[https://github.com/FlowsheetSimulation/Dyssol-open]
|-
|[[DWSIM]]
|Daniel Medeiros, Gustavo León and Gregor Reichert
|Process simulator
|Windows, Linux, macOS, Android, iOS
|open-source ([https://dwsim.inforside.com.br/wiki/index.php?title=Licensing GPLv3]), freemium
|[http://dwsim.inforside.com.br]
|-
|[[EMSO simulator|EMSO]]
|ALSOC Project
|Modelling, simulation and optimisation, steady state and dynamic, equation oriented with open source models
|Windows, Linux
|closed-source (UI), open-source (library)[https://www.enq.ufrgs.br/trac/alsoc/wiki/EMSO]
|
[http://www.enq.ufrgs.br/trac/alsoc]
|-
|EQ-COMP
|Amit Katyal
|Vapor Liquid Equilibrium Software
|Software-as-a-Service
|closed-source
|[http://www.eq-comp.com <nowiki>[59]</nowiki>]
|-
|FlowTran
|FlowTran
|Transient single phase pipeline simulation
|
|closed-source
|[http://www.flowtran.com.au/]
|-
|GAMS
|GAMS
|General Algebraic Modeling System (GAMS)
|Windows, Linux, Mac OS, Solaris
|closed-source
|[https://www.gams.com/]
|-
|gPROMS
|PSE Ltd
|Advanced process simulation and modelling
|
|closed-source
|[http://www.psenterprise.com/]
|-
|[[HSC Sim]]
|[[Outotec|Outotec Oyj]] 
|Advanced process simulation and modelling, Flowsheet simulation
|Windows
|closed-source
|[https://web.archive.org/web/20141208063622/http://www.outotec.com/en/Products--services/HSC-Chemistry/Calculation-modules/Sim--process-simulation/]
|-
|HYD-PREDIC
|Amit Katyal
|Multiphase flow assurance and hydrate modelling
|Software-as-a-Service
|closed-source
|[https://www.eq-comp.com/hyd-predic-hydrate-prediction-flow-assurance-software/]
|-
|HYDROFLO
|Tahoe Design Software
|Piping System Design with Steady State Analysis
|Windows
|closed-source
|[http://www.tahoesoft.com/]
|-
|Indiss Plus'''®'''
|[[Corys TESS|Corys]]
|Dynamic process simulator for hydrocarbons, chemicals
|Windows
|closed-source
|[http://www.corys.com/]
|-
|ICAS
|KT-Consortium
|Integrated Computer-Aided System
|Windows
|closed-source
|[https://www.kt.dtu.dk/english/research/kt-consortium/software]
|-
|IDEAS
|Andritz Automation
|Dynamic simulator for pulp, oil sands, potash, and hard rock mining
|Windows
|closed-source
|[http://www.andritzautomation.com/index.php?page=about_us&subpage=ideas]
|-
|iiSE Simulator
|iiSE company
|Equation oriented chemical process simulator and optimizer 
|Windows, Linux
|closed-source
|[http://iise.ltd/]
|-
|ITHACA
|Element Process
|General purpose dynamic chemical process simulator
|Windows
|closed-source
|[https://elementprocess.com.au/ithaca/]
|-
|JADE
|[[GSE Systems]]
|Dynamic process simulation
|Windows
|closed-source
|[https://www.gses.com/products/systems/platforms-development-tools/]
|-
|[[JModelica.org]]
|Modelon AB
|Process simulation
|Windows, Linux, macOS
|closed-source<ref name="jmodelica_2020_closed"/>
|[https://jmodelica.org/]
|-
|K-Spice
|[[Kongsberg Digital]]
|Dynamic process simulation
|Windows
|closed-source
|[https://web.archive.org/web/20140315044150/http://www.kongsberg.com/en/kogt/offerings/software/k-spice/]
|-
|LedaFlow
|[[Kongsberg Digital]]
|Transient multiphase pipeline simulation
|Windows
|closed-source
|[https://www.kongsberg.com/ledaflow]
|-
|LIBPF
|simevo
|C++ Library for process flowsheeting
|Linux, Windows, macOS
|closed-source
|[https://libpf.com/sdk/]
|-
|METSIM
|Metsim International
|General-purpose dynamic and steady state process simulation system
|Windows
|closed-source
|[http://www.metsim.com]
|-
|[[Mimic Simulation Software]]
|MYNAH Technologies
|First-principles dynamic simulator built for software acceptance testing and operator training systems
|Windows
|closed-source
|[https://www.mynah.com/product/mimic]
|-
|Mobatec Modeller
|Mobatec
|Advanced Dynamic (Steady-State) Process Modelling Environment
|Windows
|closed-source
|[https://www.mobatec.nl/web/products/mobatec-modeller/]
|-
|NAPCON ProsDS
|Neste Engineering Solutions Oy
|Dynamic process simulation
|Windows
|closed-source
|[https://www.napconsuite.com/product/napcon-simulator/]
|-
|[[OLGA (technology)|OLGA]]
|[[Schlumberger]]
|Transient multiphase pipeline simulation
|Windows
|closed-source
|[https://www.software.slb.com/products/olga]
|-
|[[OLI Analyzer]]
|OLI Systems, Inc.
|Chemical phase equilibrium simulation featuring electrolytes
|Windows
|closed-source

|[https://www.olisystems.com/]
|-
|Omegaland
|OMEGA Simulation
|Dynamic process simulation
|Windows
|closed-source
|[https://www.omegasim.co.jp/contents_e/product/ol/]
|-
|OptiRamp
|Statistics & Control, Inc.
|Real-time Process Simulation and Optimization, Multi variable Predictive Control
|Windows 
|closed-source
|[https://web.archive.org/web/20170919004510/http://www.stctrl.com/]
|-
|[[OpenModelica]]
|Open-Source Modelica Consortium
|General purpose simulation
|Linux, macOS
|open-source ([https://github.com/OpenModelica/OpenModelica/blob/868b628a698d3de84ca2cfda0aba5f577f4ee144/OSMC-License.txt OSMC-PL 1.2])
|[https://www.openmodelica.org/]
|-
|PD-PLUS
|Deerhaven Technical Software
|Steady-State Modeling of Chemical, Petrochemical, and Refining Processes
|Windows
|closed-source
|[http://www.deerhaventech.com/]
|-
|PIPE-FLO Professional
|[[Engineered Software Inc.]]
|Piping System Simulation and Design
|Windows
|closed-source
|[http://www.eng-software.com]
|-
|PIPEFLO
|Schlumberger
|Steady state multiphase flowline simulation
|Windows
|closed-source
|[https://www.software.slb.com/support/product]
|-
|PIPESIM
|[[Schlumberger]]
|Steady state multiphase flowline simulation
|Windows
|closed-source
|[https://www.software.slb.com/support/product]
|-
|PEL Suite
|PEL Software
|Steady state process simulation
|Windows
|closed-source
|[http://www.pelsoftware.com/products.php]
|-
|Petro-SIM
|[[KBC Advanced Technologies]]
|Dynamic process simulation
|Windows
|closed-source
|[https://www.kbc.global/software/process-simulation-software/]
|-
|PETROX
|[[Petrobras]]
|In-house steady state refining process simulator<ref name="aiche_2013_petrox"/>
|Windows
|closed-source
|N/A
|-
|Power Plant Simulator & Designer
|KED GmbH
|Basic Engineering and Dynamic process simulation for power plants
|Windows
|closed-source
|[http://www.powerplantsimulator.com/]
|-
|Process Studio
|Protomation
|Simulation Suite for Modeling, Engineering & Training
|Windows
|closed-source
|[http://www.protomation.com/]
|-
|Prode Properties
|Prode Software
|Thermodynamic Library, Properties of pure fluids and mixtures, Multi phase Equilibria + process simulation
|Windows
|closed-source
|[https://www.prode.com/en/ppp.htm]
|-
|Prode Process Interface
|Prode Software
|Process simulation, optimization realtime control
|Windows
|closed-source
|[https://www.prode.com/en/opcgashydrocarbon.htm]
|-
|[[ProMax]]
|Bryan Research & Engineering
|Process simulator capable of modeling oil & gas plants, refineries, and many chemical plants
|Windows
|closed-source
|[https://bre.com/ProMax-Main.aspx]
|-
|ProPhyPlus
|ProSim
|Thermodynamic calculation software
|Windows
|closed-source
|[https://www.prosim.net/en/product/prophyplus-thermodynamic-calculations/]
|-
|ProSec
|ProSim
|Simulation of brazed plate fin heat exchangers
|Windows
|closed-source
|[https://www.prosim.net/en/product/prosec-simulation-of-brazed-plate-fin-heat-exchangers/]
|-
|ProSim DAC
|ProSim
|Dynamic adsorption column simulation
|Windows
|closed-source
|[https://www.prosim.net/en/product/prosim-dac-dynamic-adsorption-column-simulation/]
|-
|ProSim HEX
|ProSim
|Heat Exchangers Simulation
|Windows
|closed-source
|[https://www.prosim.net/en/product/prosimhex-heat-exchangers-simulation/]
|-
|ProSimPlus
|ProSim
|Steady-state simulation and optimization of processes
|Windows
|closed-source
|[https://www.prosim.net/en/product/prosimplus-steady-state-simulation-and-optimization-of-processes/]
|-
|ProSimulator
|Sim Infosystems
|Process and Power plant simulation  
|Windows
|closed-source
|[http://www.siminfosys.com/]
|-
|[[PRO/II]]
|[[Aveva|AVEVA]]
|Steady state process simulation
|Windows
|closed-source
|[http://software.invensys.com/products/simsci/design/pro-ii]
|-
|[[ROMeo (process optimizer)|ROMeo]]
|[[Aveva|AVEVA]]
|Process optimization
|Windows
|closed-source
|[https://www.aveva.com/en/products/process-optimization/]
|-
|Reaction Lab
|Scale-up Systems
|Chemist-oriented kinetic modeling and reaction optimization
|Windows
|closed-source
|[https://www.scale-up.com/ReactionLab]
|-
|RecoVR
|VRTech
|Industrial wastewater management
|Windows
|closed-source
|[https://web.archive.org/web/20180907005133/http://vrtech.com.br/pt/recovr/]
|-
|REX
|Optience
|Reactor Optimization and Kinetic Estimation
|Windows
|closed-source
|[http://www.optience.com/rex/]
|-
|SimCentral
|[[Aveva|AVEVA]]
|Steady state, Fluid flow and Dynamic process simulator.
|Windows
|closed-source
|[http://software.invensys.com/products/simsci/design/simcentral]
|-
|SimCreate
|TSC Simulation
|Real time, first principle and generic operator training simulations, plant specific emulations and OPC for live plant connections.
|Windows
|closed-source
|[http://www.tscsimulation.co.uk]
|-
|Simulis Thermodynamics
|ProSim
|Mixture properties and fluid phase equilibria calculations
|Windows
|closed-source
|[https://www.prosim.net/en/product/simulis-thermodynamics-mixture-properties-and-fluid-phase-equilibria-calculations/]
|-
|SolidSim (Now in Aspen Plus<ref name="mergr_20120209_prosim"/><ref name="colan_2020_solidsim"/>)
|SolidSim Engineering GmbH
|Flowsheet simulation of solids processes
|Windows
|closed-source
|[https://www.aspentech.com/en/resources/press-releases/aspentech-announces-availability-of-aspenonert-v8-process-optimization-software15032387367/]
|-
|SPEEDUP
|[[Aspen Technology]]
|Dynamic process simulation
|Unix, Windows
|closed-source
|[https://web.archive.org/web/19970126132506/http://www.aspentech.com/products/software/speedup/speedup.html]
|-
|SuperPro Designer
|[[Intelligen]]
|Batch and continuous process simulation.
|Windows
|closed-source
|[https://www.intelligen.com/products/superpro-overview/]
|-
|[[SysCAD]]
|KWA Kenwalt Australia
|Steady-state and dynamic process simulation
|Windows
|closed-source
|[http://www.syscad.net/]
|-
|UniSim Design Suite
|[[Honeywell]]
|Process simulation and optimization 
|Windows
|closed-source
|[https://www.honeywellprocess.com/en-US/explore/products/advanced-applications/unisim/Pages/unisim-design-suite.aspx]
|-
|UniSim Competency Suite
|[[Honeywell]]
|Opertator Competency Management and Training
|Windows
|closed-source
|[https://www.honeywellprocess.com/en-US/explore/products/advanced-applications/unisim/unisim-competency-suite/Pages/default.aspx]
|-
|Usim Pac
|Caspeo
|Steady-state simulator for the mineral industry, biorefineries and waste treatment
|Windows
|closed-source
|[http://www.caspeo.net/usimpac]
|-
|Virtuoso
|[[John Wood Group|Wood PLC]]
|Multiphase dynamic process simulator for oil & gas production
|Windows
|closed-source
|[https://www.woodgroup.com/what-we-do/view-by-products-and-services/digital-solutions/virtuoso]
|-
|VMG Symmetry
|[[Schlumberger]]
|Steady state simulation, dynamic process simulation, transient multiphase flowline simulation
|Windows
|closed-source
|[http://virtualmaterials.com/VMGSim]
|-
|[[Wolfram SystemModeler]]
|[[Wolfram Research]]
|[[Modelica]]-based Dynamic multidomain modelling (mechanical, electrical, chemical)
|Windows, Mac, Linux
|closed-source
|[http://www.wolfram.com/system-modeler]
|}

== See also ==
* [[Chemical engineering]]
* [[Process simulation]]
* [[Process engineering]]

== References ==
{{reflist|refs=

<ref name="jmodelica_2020_closed">{{cite web
 |title         = JModelica Closed Source Announcement
 |url           = https://jmodelica.org/
 |archive-url   = https://web.archive.org/web/20200213102643/https://jmodelica.org/
 |url-status    = dead
 |archive-date  = 13 Feb 2020
 |access-date   = 13 Feb 2020
}}</ref>

<ref name="aiche_2013_petrox">{{cite conference
 |url           = https://aiche.confex.com/aiche/s13/webprogram/Paper294028.html
 |title         = Petrobras in-House Process Simulator As a Strategic Advantage
 |last1         = Barbosa
 |first1        = Renato A.
 |date          = 1 May 2013
 |publisher     = [[American Institute of Chemical Engineers|AIChE]]
 |conference    = 13 AIChE Spring Meeting, San Antonio, TX
 |id            = 294028
}}</ref>

<ref name="mergr_20120209_prosim">{{Cite web
 |title         = SolidSim Engineering was acquired by Aspen Technology on February 9, 2012
 |url           = https://mergr.com/solidsim-engineering-acquired-by-aspen-technology
 |access-date   = 24 Dec 2020
 |website       = mergr.com
 |archive-url   = https://web.archive.org/web/20201224230635/https://mergr.com/solidsim-engineering-acquired-by-aspen-technology
 |archive-date  = 24 Dec 2020
}}</ref>

<ref name="colan_2020_solidsim">{{cite web
 |title         = Solidsim
 |url           = https://www.colan.org/experiences-projects/solidsim/
 |access-date   = 24 Dec 2020
 |archive-url   = https://web.archive.org/web/20201029221551/https://www.colan.org/experiences-projects/solidsim/
 |archive-date  = 29 Oct 2020
 |quote         = SolidSim Engineering was absorbed by Aspen Technology Inc. with the unit operations of SolidSim made available in Aspen Plus.
}}</ref>

}}
* Seader, J.D., Seider, W.D. and Pauls, A.C.: Flowtran Simulation – An Introduction, 2nd Edition, CACHE (1977).
* Douglas, J.M.: Conceptual Design of Chemical Processes, McGraw-Hill, NY, USA (1988).
* Smith, R., Chemical process Design and Integration, Wiley, Chichester, UK (2005).
* Seider, W.D., Seader, J.D., Lewin, D.R. and Widagdo, S. Product and Process Design Principles: Synthesis, Analysis and Design, 3rd Ed., Wiley, Hoboken, NJ, USA (2015)

{{DEFAULTSORT:List Of Chemical Process Simulators}}
[[Category:Chemical engineering software]]
[[Category:Lists of software|Chemical Process Simulators]]